Question

Which statement about cystic fibrosis is true?(1 point) Responses Cystic fibrosis is caused by a deletion of one codon in the DNA molecule. Cystic fibrosis is caused by a deletion of one codon in the DNA molecule. Carriers have an advantage over people who do not have the cystic fibrosis mutation. Carriers have an advantage over people who do not have the cystic fibrosis mutation. Cystic fibrosis is caused by a mutation in which a dominant allele replaces a recessive allele. Cystic fibrosis is caused by a mutation in which a dominant allele replaces a recessive allele. Cystic fibrosis affects a person's ability to make normal red blood cells

Answers

GPT-4o mini
The statement that is true regarding cystic fibrosis is:

**Carriers have an advantage over people who do not have the cystic fibrosis mutation.**

Cystic fibrosis is caused by a mutation in the CFTR gene, specifically a deletion of three nucleotides, which results in the loss of a phenylalanine residue at position 508 of the CFTR protein (not a deletion of one codon), and it is inherited in an autosomal recessive manner, meaning that it is caused by two recessive alleles, not by a dominant replacing a recessive. Cystic fibrosis primarily affects the lungs and digestive system, not the production of red blood cells. Carriers of the cystic fibrosis gene mutation may have some protection against certain diseases, such as typhoid fever.