The correct response is:
It denied Congress the power to regulate slavery in the territories.
The Supreme Court's decision in Dred Scott v. Sandford (1857) ruled that Congress lacked the authority to prohibit slavery in the territories, which exacerbated tensions between the North and South and increased sectionalism. This decision nullified the Missouri Compromise and angered many in the North, who opposed the expansion of slavery, while it was welcomed by pro-slavery advocates in the South.