To simplify the expression \( 4 - 22 - 3 \), we perform the operations step-by-step:
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Start with the expression: \[ 4 - 22 - 3 \]
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First, subtract \( 22 \) from \( 4 \): \[ 4 - 22 = -18 \]
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Next, subtract \( 3 \) from \( -18 \): \[ -18 - 3 = -21 \]
Thus, \( 4 - 22 - 3 = -21 \).
Since none of the provided responses (−16, −8, 8, 16) equal -21, it looks like there may be a mistake in the original expression or the provided options. The resulting value from the expression is \(-21\).