The best statement of the Law of Conservation of Energy from the options provided is:
The amount of energy put out by a simple machine must equal the amount of energy put into the machine.
This statement accurately reflects the principle that energy cannot be created or destroyed, only transformed from one form to another. However, it is important to note that in real-world scenarios, energy losses due to friction, heat, and other factors are often present, leading to the output being less than the input when considering inefficiencies.