Question
A DNA segment has base order TCG TAT AAC. Which copy exhibits an insertion mutation without a frameshift?(1 point)
Responses
TCC TAT AAC
TCC TAT AAC
TCG TAT AC
TCG TAT AC
TCG TAT GAAC
TCG TAT GAAC
TCG CCG TAT AAC
Responses
TCC TAT AAC
TCC TAT AAC
TCG TAT AC
TCG TAT AC
TCG TAT GAAC
TCG TAT GAAC
TCG CCG TAT AAC
Answers
GPT-4o mini
To determine which copy exhibits an insertion mutation without a frameshift, we need to understand how mutations can affect the DNA sequence.
A **frameshift mutation** occurs when nucleotides are added or removed from the DNA sequence in a number that is not a multiple of three, which shifts the reading frame of the sequence. An **insertion mutation** that does not cause a frameshift would involve the addition of nucleotides in multiples of three.
The original sequence is:
**TCG TAT AAC**
Now, let's analyze the given options:
1. **TCC TAT AAC** - This is a substitution mutation, not an insertion.
2. **TCG TAT AC** - This sequence has one nucleotide deleted, which is not an insertion.
3. **TCG TAT GAAC** - This sequence has "GA" inserted between "TAT" and "AAC." Since "GA" is 2 nucleotides, it adds a non-multiple of three, which causes a frameshift.
4. **TCG CCG TAT AAC** - This sequence adds "CCG" before "TAT." Since "CCG" is 3 nucleotides long, this is a valid insertion mutation that does not change the reading frame.
Based on this analysis, the correct answer is:
**TCG CCG TAT AAC**
A **frameshift mutation** occurs when nucleotides are added or removed from the DNA sequence in a number that is not a multiple of three, which shifts the reading frame of the sequence. An **insertion mutation** that does not cause a frameshift would involve the addition of nucleotides in multiples of three.
The original sequence is:
**TCG TAT AAC**
Now, let's analyze the given options:
1. **TCC TAT AAC** - This is a substitution mutation, not an insertion.
2. **TCG TAT AC** - This sequence has one nucleotide deleted, which is not an insertion.
3. **TCG TAT GAAC** - This sequence has "GA" inserted between "TAT" and "AAC." Since "GA" is 2 nucleotides, it adds a non-multiple of three, which causes a frameshift.
4. **TCG CCG TAT AAC** - This sequence adds "CCG" before "TAT." Since "CCG" is 3 nucleotides long, this is a valid insertion mutation that does not change the reading frame.
Based on this analysis, the correct answer is:
**TCG CCG TAT AAC**