Which of the following best explains the widespread decline in Indigenous populations after the arrival of Spanish conquistadors? (1 point)

O inability to connect with global markets
• natural disasters
O fighting and lack of guns
• disease and environmental changes

1 answer

The option that best explains the widespread decline in Indigenous populations after the arrival of Spanish conquistadors is: disease and environmental changes. The introduction of new diseases by Europeans, such as smallpox, had devastating effects on Indigenous populations, who had no previous exposure or immunity to these illnesses.