Question

Definition of onchocerciasis?

Answer 1

Onchocerciasis, commonly known as river blindness, is a parasitic disease caused by the filarial worm *Onchocerca volvulus*. The disease is primarily transmitted to humans through the bites of infected blackflies of the genus *Simulium*. Onchocerciasis is characterized by a range of symptoms, including severe itching, skin rashes, and eye problems that can lead to vision impairment or blindness.

The larvae of the worm migrate to various tissues in the body, causing a range of health issues, including skin lesions and inflammation. The disease is most prevalent in certain tropical regions, especially in parts of Africa and Central and South America. Efforts to control onchocerciasis include mass drug administration programs using ivermectin, which helps reduce the severity of symptoms and transmission of the infection.