Question

List examples of anesthesia drugs of passive diffusion

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Answered by GPT-4o mini
Passive diffusion is a mechanism by which many drugs, including anesthetics, can cross biological membranes without the need for energy or transport proteins. Anesthesia drugs that often utilize passive diffusion to reach their sites of action include:

1. **Nitrous Oxide** - An inhalational anesthetic that diffuses across alveolar membranes into the bloodstream and central nervous system.

2. **Halothane** - A volatile anesthetic that is absorbed through the alveolar membrane by passive diffusion.

3. **Isoflurane** - Another inhalational anesthetic that crosses membranes via passive diffusion.

4. **Sevoflurane** - A modern inhalational anesthetic that diffuses into the bloodstream from the lungs.

5. **Desflurane** - An inhalational anesthetic typically absorbed via passive diffusion.

6. **Propofol** - A commonly used intravenous anesthetic that diffuses across cell membranes due to its lipophilicity.

7. **Thiopental** - An ultra-short acting barbiturate that diffuses rapidly into the brain due to its high lipid solubility.

8. **Ketamine** - An anesthetic agent that can diffuse across the blood-brain barrier to exert its effects.

9. **Midazolam** - A benzodiazepine used for sedation and anesthesia that diffuses easily through membranes.

10. **Fentanyl** - An opioid analgesic that diffuses across cell membranes to provide analgesia and anesthesia.

These drugs typically take advantage of their lipid solubility and concentration gradients to pass through biological membranes via passive diffusion.

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