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Question
A scientist is tracking the evolution of a gene in giant African snails that determines the direction of the spiral in shells. The following DNA sequence data was taken from a population of giant African snails:



DNA from Snail Parent for Corkscrew Shell Gene:

A

A

T

G

C

G

T

A

T

G

T

T

A

C

G

C

A

T

A

C



DNA from Snail Offspring #1 for Corkscrew Shell Gene:

A

A

T

T

C

G

T

A

T

G

T

T

A

A

G

C

A

T

A

C



DNA from Snail Offspring #2 for Corkscrew Shell Gene:

A

A

T

C

G

T

A

T

G

T

T

A

G

C

A

T

A

C



DNA from Snail Offspring #3 for Corkscrew Shell Gene:

A

A

T

G

C

G

T

A

T

G

G

T

T

A

C

G

C

A

T

A

C

C



DNA from Snail Offspring #4 for Corkscrew Shell Gene:

A

A

T

G

C

G

T

A

T

G

T

T

A

C

G

C

A

T

A

C



Compared to the parent’s DNA sequence, identify the snail offspring that has a substitution mutation in the corkscrew shell gene.

(1 point)
Responses

Offspring #4
Offspring #4

Offspring #3
Offspring #3

Offspring #1
Offspring #1

Offspring #2
Offspring #2
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Answers

GPT-4o mini
To identify the snail offspring that has a substitution mutation in the corkscrew shell gene, we need to compare the DNA sequences from the parent and each of the offspring.

The parent’s DNA sequence is:
```
A A T G C G T A T G T T A C G C A T A C
```

Now, let's look at the offspring sequences:

- **Offspring #1**:
```
A A T T C G T A T G T T A A G C A T A C
```
(Difference: 4th base - G to T)

- **Offspring #2**:
```
A A T C G T A T G T T A G C A T A C
```
(Difference: 4th base - G to C)

- **Offspring #3**:
```
A A T G C G T A T G G T T A C G C A T A C
```
(Difference: 10th base - T to G)

- **Offspring #4**:
```
A A T G C G T A T G T T A C G C A T A C
```
(No differences, identical to parent)

Comparing each sequence, we see that both **Offspring #1** and **Offspring #2** exhibit substitutions in the 4th position, while **Offspring #3** exhibits a substitution mutation at the 10th position. **Offspring #4** is identical to the parent.

Thus, the offspring that has a substitution mutation in the corkscrew shell gene could refer to any of **Offspring #1**, **Offspring #2**, or **Offspring #3**, depending on whether they're looking for a substitution specifically in terms of base pairs.

However, if the question narrowly asks for *one* specific offspring with a substitution mutation, then the **best answer would be Offspring #1 or Offspring #2**, as both show a substitution compared to the parent's sequence.

Final answer choice based on the possible choices given would be:
- **Offspring #1** (A substitution of 'G' to 'T')

However, you could argue the validity of either; thus, you may need the context provided in the question or assumptions you're making based on preferred mutations.

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