Which of the following BEST describes how the Spanish and Hernando DeSoto impacted the Native Americans living in the southeastern region of North America?

A. Native Americans benefitted from learning about new technologies from the Europeans.
B. They formed a strong alliance and became trading partners.
C. The Native Americans were introduced to new foods.
D. Thousands of Native Americans died as a result of diseases spread by contact with Europeans.

1 answer

The option that BEST describes how the Spanish and Hernando DeSoto impacted the Native Americans living in the southeastern region of North America is:

D. Thousands of Native Americans died as a result of diseases spread by contact with Europeans.

While there were other impacts, such as the introduction of new foods and technologies, the devastating effect of diseases brought by Europeans led to significant population declines among Native American groups.