which of the strands (lagging or leading) requires primase to act more frequently?

a. the leading strand
b. the lagging strand

1 answer

b. the lagging strand

The lagging strand requires primase to synthesize RNA primers more frequently because it is synthesized in short segments called Okazaki fragments, which necessitate the addition of a new primer for each fragment. In contrast, the leading strand is synthesized continuously and requires only a single RNA primer at the beginning of the replication process.