Because alcohol is a depressant,

which drug would be the most
harmful when used with it?
barbiturates
chewing tobacco
marijuana
tar

1 answer

Barbiturates would be the most harmful when used with alcohol. Both substances are central nervous system depressants, and their combined effects can lead to severe respiratory depression, increased sedation, and a higher risk of overdose. Combining these drugs can be extremely dangerous and potentially life-threatening. Chewing tobacco, marijuana, and tar do not have the same level of dangerous interaction with alcohol as barbiturates do.