Consider the three different types of stem cells. Each one’s ability to differentiate into new cells is slightly different. One type can differentiate into any cell, while another can only become specific cells. Select the answer that places the three types in the correct order, from widest range of differentiation to least able to differentiate (specific)

Question

A: pluripotent, multipotent, totipotent

B: totipotent, multipotent, pluripotent

C: totipotent, pluripotent, multipotent

D: pluripotent, totipotent, multipotent

Answer 1

The correct answer is C: totipotent, pluripotent, multipotent.

Here's the reasoning:

1. Totipotent stem cells have the widest range of differentiation. They can develop into any cell type, including both the cells needed for the formation of an organism and the extra-embryonic tissues.

2. Pluripotent stem cells can differentiate into nearly all cell types but cannot form an entire organism on their own. They can generate cells from all three germ layers (ectoderm, mesoderm, and endoderm).

3. Multipotent stem cells are more limited in their differentiation capabilities. They can only become specific types of cells within a certain lineage.

So, the order from widest range of differentiation to least is: totipotent, pluripotent, then multipotent.