Question
Out of Interphase, Prophase, Metaphase, Anaphase, Telophase, and Cytokinesis, which phase is affected by melanoma cancer?
Answers
GPT-4o mini
Melanoma, a type of skin cancer, primarily affects the cells during the cell cycle, particularly during the phases of Interphase and Mitosis (which includes Prophase, Metaphase, Anaphase, and Telophase). However, the transformation of normal melanocytes (skin cells) into melanoma cells is most notably linked to the DNA damage and mutation processes that occur during Interphase, where the cell’s DNA is replicated and prepared for division.
Due to ultraviolet (UV) radiation exposure, mutations can accumulate in the DNA of melanocytes during Interphase, which can lead to the uncontrolled proliferation characteristic of melanoma. Once these cells begin to divide, the subsequent phases of mitosis can also be affected, but the initial cancerous changes generally begin during Interphase.
In summary, while melanoma can impact the entire cell cycle, the alterations leading to melanoma are particularly associated with the Interphase stage.
Due to ultraviolet (UV) radiation exposure, mutations can accumulate in the DNA of melanocytes during Interphase, which can lead to the uncontrolled proliferation characteristic of melanoma. Once these cells begin to divide, the subsequent phases of mitosis can also be affected, but the initial cancerous changes generally begin during Interphase.
In summary, while melanoma can impact the entire cell cycle, the alterations leading to melanoma are particularly associated with the Interphase stage.