The correct response is: Crusaders attacked and subdued Constantinople, never making it to the Holy Lands and further dividing West and East.
The Fourth Crusade (1202–1204) is best known for its diversion from its original goal of reaching the Holy Land. Instead, the Crusaders ended up attacking and capturing Constantinople, the capital of the Byzantine Empire, which had significant long-term implications for the relationship between the Eastern Orthodox and Roman Catholic Churches.