The most accurate choice from the options provided is:
transfer one specifically selected gene, instead of thousands, from one organism to another.
This reflects the capability of genetic engineering to target specific genes for transfer between organisms. The other statements are either overly broad or not entirely accurate in their claims. For example, while genetic engineering has contributed to making crops more resistant to pests, it has not universally made all crops permanently resistant. Additionally, while genetic engineering can help in addressing food shortages, it has not solved the issue entirely. Furthermore, genetic exchange can occur between different species through techniques like transgenic modifications, contrary to the notion presented in the fourth option.