The primary reason Jefferson and his Democratic-Republican Party opposed policies that favored manufacturing and trade is best captured by:
c. The Democratic Republicans felt they gave power only to a wealthy few in the North.
The Democratic-Republicans were generally supportive of agrarian interests and believed that a strong emphasis on manufacturing and trade concentrated economic power and influence in a few wealthy northern industrialists, which they saw as detrimental to the interests of the broader population, particularly farmers in the South. They favored a more decentralized economy based on agriculture, which they believed was the backbone of American democracy and individual liberty.