The correct response is:
The number of protons in the atom changes.
When an alpha particle (which consists of 2 protons and 2 neutrons, effectively a helium nucleus) is emitted from a nucleus, the original atom loses 2 protons and 2 neutrons, resulting in a change in the atomic number. This change in the number of protons means that the atom is transformed into a different element, leading to transmutation.