The events that led to the Second Seminole War include:
-
the signing of the Treaty of Payne’s Landing - This treaty was meant to remove the Seminole from Florida, leading to resistance.
-
the harboring of runaway slaves - The Seminole were known to provide refuge to runaway slaves, which heightened tensions with slaveholding states.
-
the signing of the Indian Removal Act - This act mandated the relocation of Native American tribes, including the Seminole, from their lands in the Southeast to designated Indian Territory west of the Mississippi River.
Thus, the correct answers are the first, second, and fifth options.