The correct explanation for the muscle fatigue you're experiencing while running as fast as you can is:
d inadequate supply of oxygen to muscle cells leads to lactic acid fermentation.
Here's why this is accurate:
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Oxygen Supply: During intense exercise, the demand for energy in muscle cells increases significantly. If the intensity of the exercise exceeds the fiber's ability to deliver oxygen quickly enough for aerobic respiration, the muscle cells will start to rely more on anaerobic pathways for ATP production.
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Lactic Acid Fermentation: When oxygen levels are low, muscle cells can convert glucose into energy through a process called anaerobic respiration (or lactic acid fermentation). This process produces ATP quickly, but it also generates lactic acid as a byproduct.
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Muscle Fatigue: The accumulation of lactic acid in the muscles leads to the burning sensation, fatigue, and eventual muscle weakness, as the lactic acid can interfere with muscle contraction processes and affect the pH levels within the cells.
In summary, it's the inadequate supply of oxygen that forces muscle cells into lactic acid fermentation, resulting in the fatigue and burning sensation you feel when you exercise intensely.