Question

Hemophilia is a hereditary bleeding disorder that primarily affects males. In 3–4 sentences, summarize why this condition typically affects males more than females. Please make your answer simple, coherent, and intended for 9th grade.

Answer 1

Hemophilia is a genetic disorder that affects the blood's ability to clot, and it is linked to genes on the X chromosome. Males have one X and one Y chromosome, so if they inherit the hemophilia gene on their single X chromosome, they will have the condition. Females have two X chromosomes, so even if one X carries the hemophilia gene, the other normal X can still produce enough clotting factors to prevent the disorder. This is why hemophilia primarily affects males.