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MUTATED DNA Sequence #2 ➔ T A C G A C C T T G G C G A C G A C T

What is the mRNA sequence? (Circle the change)
amino acid sequence?
Will there likely be effects? What type of mutation is this? ______________________________

1 answer

To find the mRNA sequence from the given DNA sequence, we first need to transcribe the DNA sequence to RNA. In RNA, adenine (A) pairs with uracil (U) instead of thymine (T).

Given DNA Sequence:

T A C G A C C T T G G C G A C G A C T

Transcribing to mRNA:

  • Replace T with A
  • Replace A with U
  • Replace G with C
  • Replace C with G

mRNA Sequence: A U G C U G G A A C C G C U G C U G A

Amino Acid Sequence

Next, we will translate the mRNA sequence into the amino acid sequence. To do this, we will use the genetic code, where each codon (three nucleotides) corresponds to an amino acid.

  • AUG - Methionine (Met)
  • CUG - Leucine (Leu)
  • GAA - Glutamic Acid (Glu)
  • CCG - Proline (Pro)
  • CUG - Leucine (Leu)
  • CUA - Leucine (Leu)

Amino Acid Sequence:

Met - Leu - Glu - Pro - Leu - Leu

Identifying Mutation Type:

Now, regarding the effects and type of mutation, there are a few points to consider:

  1. If the change in the DNA sequence results in a change in the amino acid sequence, it might indicate a missense mutation (a single nucleotide change results in a codon that codes for a different amino acid).

  2. If the change results in a stop codon, it would be a nonsense mutation, which typically has more detrimental effects.

  3. If the mutation does not change the amino acid sequence, it is called a silent mutation.

  4. If the sequence results in a frameshift due to deletion or insertion, it could drastically change the downstream amino acid sequence.

In this case, since we're assuming you've specified a mutated sequence, you'll need to compare it to the original sequence (not provided) to identify specifically what has been altered and whether it causes a notable change in the amino acid sequence.

Conclusion on Likely Effects:

  • If any of the amino acids in the sequence has changed compared to an original sequence, there could be effects on protein function.
  • The type of mutation would need to be identified by comparing to the original sequence, but some potential names can include missense, nonsense, or silent mutations depending on the nature of the change.

If you provide the original (non-mutated) DNA sequence, I could give you a more exact answer on the mutation type and the likely effects.