In the number 12,345,000, the largest place value is in the millions place. The number can be broken down as follows:
- 1 is in the ten million place,
- 2 is in the million place,
- 3 is in the hundred thousand place,
- 4 is in the ten thousand place,
- 5 is in the thousand place.
The largest place value is therefore 10 million, represented by the digit 1 in the ten million place.