The correct statement about the number of protons and neutrons in a nuclear change is:
The relative numbers of protons and neutrons can differ before and after the change, but the total number of those particles remains the same.
In a nuclear reaction, protons and neutrons can be converted into each other (for example, during beta decay), which means their relative numbers can change. However, the total number of nucleons (protons + neutrons) in a nuclear reaction is generally conserved.