To identify the set with the stronger interaction between two sets of electrically charged objects, the student should ask:
Are the objects both positively charged or both negatively charged?
This question directly addresses the nature of the interaction between the charges. According to Coulomb's law, like charges repel each other, and opposite charges attract. If both objects in a set are of the same charge (either both +1 or both -1), they will repel each other, while if they are of opposite charges, they will attract. Thus, knowing whether the charges are the same or different will help to determine the strength and type of the interaction.
The other questions regarding mass, distance, or size are not directly relevant to determining the strength of the electrostatic interaction, as strength is more fundamentally related to the nature of the charges involved.