To find the slope (m) of the line passing through the points \((x_1, y_1) = (1, -5)\) and \((x_2, y_2) = (4, 1)\), we can use the slope formula:
\[ m = \frac{y_2 - y_1}{x_2 - x_1} \]
Substituting in our points:
\[ m = \frac{1 - (-5)}{4 - 1} = \frac{1 + 5}{3} = \frac{6}{3} = 2 \]
Thus, the slope of the line is 2.