The correct answer is D. Prokaryotes do not store their genes in a nucleus like eukaryotes do.
This difference relates to the cellular organization of prokaryotes and eukaryotes. Prokaryotes, such as bacteria, have their genetic material located in the cytoplasm as a single circular DNA molecule, while eukaryotes have their DNA enclosed within a membrane-bound nucleus. The other options contain inaccuracies regarding gene regulation and transcription processes.