To find the numerical equivalent of the expression \( 25 \cdot 2^{-2} \), we can first simplify \( 2^{-2} \):
\[ 2^{-2} = \frac{1}{2^2} = \frac{1}{4} \]
Now we can substitute this back into the expression:
\[ 25 \cdot 2^{-2} = 25 \cdot \frac{1}{4} \]
Next, we perform the multiplication:
\[ 25 \cdot \frac{1}{4} = \frac{25}{4} \]
Thus, the numerical equivalent of the expression \( 25 \cdot 2^{-2} \) is:
\[ \frac{25}{4} = 6.25 \]
So the final answer is:
\[ \boxed{6.25} \]