The stage of mitosis characterized by microtubules pulling replicated chromosomes apart and separating them into sister chromatids is called anaphase. During anaphase, the sister chromatids are pulled toward opposite poles of the cell, ensuring that each daughter cell will receive an identical set of chromosomes.
Which stage of mitosis is characterized by microtubules pulling replicated chromosomes apart and separating them into sister chromatids?
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The phase of mitosis characterized by each pair of sister chromatids moving to opposite sides of the cell is called anaphase. During this stage, the sister chromatids are separated and pulled toward opposite poles of the cell by the spindle fibers. This ensures that each daughter cell will receive an equal and identical set of chromosomes when the cell divides.
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Telophase is the final stage of mitosis, occurring after anaphase. During telophase, several key events take place:
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Chromosome Decondensation: The separated sister chromatids, now individual chromosomes, begin to decondense back into chromatin, making them less visible under a light microscope.
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Nuclear Envelope Formation: The nuclear envelopes re-form around each set of chromosomes at the two poles of the cell, resulting in the formation of two distinct nuclei.
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Nucleolus Reappearance: The nucleoli, which may have disappeared during earlier phases of mitosis, reappear within the newly formed nuclei.
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Spindle Fiber Disassembly: The mitotic spindle, which is made up of microtubules, begins to break down and disassemble.
Telophase sets the stage for cytokinesis, the final process of cell division, where the cytoplasm of the parent cell divides to form two separate daughter cells, each with a complete set of chromosomes.
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Metaphase is the stage of mitosis that follows prophase and precedes anaphase. During metaphase, several important events occur:
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Chromosome Alignment: The chromosomes, which have already been replicated and condensed, align along the metaphase plate (the equatorial plane of the cell). This alignment is crucial for ensuring that each daughter cell will receive an identical set of chromosomes.
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Spindle Fiber Attachment: Microtubules of the mitotic spindle, which were formed during prophase, attach to the kinetochores (protein structures) located on the centromeres of each chromosome. This attachment is essential for the movement of chromosomes during the next phase of mitosis (anaphase).
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Tension Generation: The spindle fibers exert tension on the kinetochores, ensuring that the chromosomes are properly aligned and are under the correct forces so they can be separated accurately.
Metaphase is a critical checkpoint in mitosis, as the cell ensures that all the chromosomes are correctly attached to the spindle apparatus and properly aligned before proceeding to the separation of sister chromatids in anaphase. Proper alignment and attachment help prevent errors in chromosome distribution, which can lead to cell division disorders.
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Prophase is the first stage of mitosis and is characterized by several key events that prepare the cell for division:
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Chromosome Condensation: During prophase, the chromatin fibers condense into visible chromosomes. Each chromosome consists of two identical sister chromatids held together at a region called the centromere.
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Nuclear Envelope Breakdown: The nuclear envelope, which encloses the nucleus, begins to break down and disappear, allowing the chromosomes to become more accessible to the spindle apparatus.
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Mitotic Spindle Formation: The mitotic spindle starts to form from the centrosomes (organelles that organize microtubules) as they move toward opposite poles of the cell. The spindle fibers, composed of microtubules, extend from the centrosomes and will eventually attach to the kinetochores of the chromosomes.
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Nucleolus Disappearance: The nucleolus, a structure within the nucleus involved in ribosome production, typically disappears during prophase.
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Chromosome Movement: As prophase progresses, the condensed chromosomes begin to move toward the center of the cell in preparation for alignment during the next phase (metaphase).
Overall, prophase is a critical phase in mitosis that sets up the subsequent steps for the accurate segregation of chromosomes into the daughter cells.