To solve the equation \(-12(x+10) = -3\), you should first isolate the term containing \(x\). The first operation that should be done is to divide both sides by \(-12\) (which is equivalent to multiplying by \(-\frac{1}{12}\)).
However, looking at the provided options, the operation to be applied to isolate \(x\) directly is divide by \(-12\), but it may not be listed explicitly in your options.
If the goal is to start simplifying the equation, the term inside the parentheses could potentially be addressed.
Since none of the provided options offer \(-12\) for division, the operation you would typically perform is the one that aims to reduce the complexity of the equation first. Among your options, multiply by \(-2\) (in the context of reducing the coefficient of \(x\) later) could relate to the original equation manipulation, but it isn't the step you'd actually perform immediately.
The correct answer based on traditional first-step analysis would be divide by \(-12\) originally, but based on available options, there could be confusion in interpretation.
If possible, please clarify if you want to pick from the options strictly as listed, or if I can assist in another way.