The correct response that highlights a key difference between the Guianas and the Caribbean islands is:
American Indian peoples live inland in the Guianas.
This reflects a significant cultural and demographic distinction, as the Guianas have a notable presence of indigenous peoples in their interior regions, while many Caribbean islands have less indigenous population due to historical colonization and migration patterns. The other options relate to linguistic and cultural aspects but do not serve as defining differences between the two regions.