To perform the calculation \(6.25 \times 10^6 - 4.73 \times 10^6\), we can subtract the coefficients since they have the same power of 10:
\[ (6.25 - 4.73) \times 10^6 \]
Calculating the coefficients:
\[ 6.25 - 4.73 = 1.52 \]
Now we can express the result in scientific notation:
\[ 1.52 \times 10^6 \]
Rounding to two decimal places remains:
\[ 1.52 \times 10^6 \]
Thus, the final answer is:
\[ \boxed{1.52 \times 10^6} \]