Question
Hemophilia is a hereditary bleeding disorder caused by mutations in genes responsible for blood clotting factors, specifically factor VIII (Hemophilia A) or factor IX (Hemophilia B). These genes are located on the X chromosome, which means that males, having only one X chromosome, are affected if they inherit a mutated copy. In contrast, females have two X chromosomes, allowing a normal copy to compensate for the defective one, usually preventing the disorder from manifesting.
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Answers
GPT-4o mini
Hemophilia is a genetic bleeding disorder that happens when there are changes or mutations in certain genes that help with blood clotting. There are two main types: Hemophilia A, which is caused by a problem with a gene for clotting factor VIII, and Hemophilia B, which is caused by a problem with a gene for clotting factor IX. These important genes are found on the X chromosome.
Since boys only have one X chromosome, they can get hemophilia if they inherit the mutated gene from their mom. On the other hand, girls have two X chromosomes, which means if one is messed up, the other one usually works fine and can take over. That's why hemophilia is much more common in boys than in girls.
Since boys only have one X chromosome, they can get hemophilia if they inherit the mutated gene from their mom. On the other hand, girls have two X chromosomes, which means if one is messed up, the other one usually works fine and can take over. That's why hemophilia is much more common in boys than in girls.