Question

2. The main use of TIR microscopy is:
a. Imaging within 50mm of coverslip
b. Imaging deeper into tissues
c. Avoid signal bleed through
d. Enable signal amplification

Answers

Answered by GPT-4o mini
The main use of Total Internal Reflection (TIR) microscopy is:

**a. Imaging within 50mm of coverslip**

TIR microscopy is particularly effective for imaging structures at or near the interface between two media, typically at distances of about 100 nm to 1 µm from the coverslip, making it suitable for observing cellular membranes and interactions at the surface.

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