The correct response is C and D.
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C. A girl uses bleach and strong detergent to wash clothes. - This can lead to harmful chemicals entering the water system, which can be detrimental to the watershed.
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D. A woman who raises vegetables uses chemical fertilizers that can wash into the watershed. - This also identifies a direct harm, as fertilizers can lead to nutrient runoff that disrupts water quality in the watershed.
In contrast, A and B describe activities that are aimed at cleaning or controlling pollution, rather than harming water quality.