Question

A line graph titled "Number of Infrared Beam Breaks by Mice Treated with CNO or Saline, by Sex". The y-axis is labeled "Number of beam breaks" and ranges from 0 to 1500 in increments of 500. The x-axis is labeled "Minutes from treatment" and ranges from -4 to 150 in increments of 14. There are four lines on the graph: "females with CNO" starts around (-4, 500), rises steadily to approximately (38, 1400), then descends gradually to approximately (150, 400); "females with saline" starts around (-4, 500) and ranges between 0 and 500 until it reaches approximately (150, 250); "males with CNO" starts around (-4, 500), rises to approximately (24, 600), then descends gradually to approximately (150, 250); "males with saline" ranges between 0 and 500 until it reaches approximately (150, 250).\[\small{500}\]
\[\small{1000}\]
\[\small{1500}\]
\[-4\]
\[10\]
\[24\]
\[38\]
\[52\]
\[66\]
\[80\]
\[94\]
\[108\]
\[122\]
\[136\]
\[150\]
To investigate the influence of certain estrogen-responsive neurons on energy expenditure, biologist Stephanie Correa et al. treated female and male mice with either saline solution or clozapine-N4-oxide (CNO), which activates the neurons. Monitoring the activity levels of the mice by measuring how frequently the animals broke infrared beams crossing their enclosures, Correa et al. found that the mice in their study showed sex-specific differences in response to neuron activation: ______
Which choice most effectively uses data from the graph to complete the assertion?
Choose 1 answer:
Choose 1 answer:
(Choice A) the four groups of mice differed greatly in their activity levels before treatment but showed identical activity levels at the end of the monitoring period.
A
the four groups of mice differed greatly in their activity levels before treatment but showed identical activity levels at the end of the monitoring period.
(Choice B) CNO-treated females showed a substantial increase and then decline in activity over the monitoring period, whereas CNO-treated males showed a substantial decline in activity followed by a steep increase.
B
CNO-treated females showed a substantial increase and then decline in activity over the monitoring period, whereas CNO-treated males showed a substantial decline in activity followed by a steep increase.
(Choice C) saline-treated females showed substantially more activity at certain points in the monitoring period than saline-treated males did.
C
saline-treated females showed substantially more activity at certain points in the monitoring period than saline-treated males did.
(Choice D) CNO-treated females showed more activity relative to saline-treated females than CNO-treated males showed relative to saline-treated males.
D
CNO-treated females showed more activity relative to saline-treated females than CNO-treated males showed relative to saline-treated males.

Answers

GPT-4o mini
The most effective choice that uses data from the graph to complete the assertion is:

**(Choice D)** CNO-treated females showed more activity relative to saline-treated females than CNO-treated males showed relative to saline-treated males.

This choice accurately reflects the observed data in the graph, where CNO-treated females show a significant increase in activity compared to saline-treated females throughout the monitoring period, whereas the CNO-treated males do not show as marked an increase compared to saline-treated males.