The primary distinction between prokaryotes and eukaryotes is that prokaryotes do not have a nucleus, whereas eukaryotes do. Additionally, eukaryotes typically possess membrane-bound organelles, including mitochondria, while prokaryotes lack these structures.
Here’s a summary of the key differences:
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Nucleus: Prokaryotes do not have a true nucleus; their genetic material is located in the nucleoid region. Eukaryotes have a well-defined nucleus that houses their DNA.
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Organelles: Eukaryotes have membrane-bound organelles (such as mitochondria and the endoplasmic reticulum), while prokaryotes do not possess such organelles.
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Size: Prokaryotic cells are generally smaller and simpler in structure compared to eukaryotic cells.
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Ribosomes: Both prokaryotes and eukaryotes have ribosomes, but the size and structure of these ribosomes differ. Prokaryotic ribosomes are 70S, while eukaryotic ribosomes are 80S.
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Genetic Material: Prokaryotic DNA is typically circular and not associated with histones (though some archaea do have histone-like proteins), while eukaryotic DNA is linear and associated with histones.
In summary, the presence or absence of a true nucleus is a fundamental difference between prokaryotes and eukaryotes.