To simplify \((10\sqrt{5})^2\), you can follow these steps:
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Square the coefficient (10): \[ 10^2 = 100 \]
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Square the radical (\(\sqrt{5}\)): \[ (\sqrt{5})^2 = 5 \]
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Combine the results: \[ (10\sqrt{5})^2 = 10^2 \cdot (\sqrt{5})^2 = 100 \cdot 5 = 500 \]
Thus, the simplified form of \((10\sqrt{5})^2\) is \(\boxed{500}\).