To simplify \( 5\sqrt{3} \times 3\sqrt{5} \), we start by multiplying the coefficients and the square roots separately.
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Multiply the coefficients: \[ 5 \times 3 = 15 \]
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Multiply the square roots: \[ \sqrt{3} \times \sqrt{5} = \sqrt{3 \times 5} = \sqrt{15} \]
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Now, combine both results: \[ 5\sqrt{3} \times 3\sqrt{5} = 15\sqrt{15} \]
Thus, the simplified form is: \[ \boxed{15\sqrt{15}} \]