To solve the quadratic equation \( x^2 - 16x + 64 = 0 \) using the perfect square trinomial pattern, we can rewrite the equation as follows:
Notice that \( x^2 - 16x + 64 \) can be factored as:
\[ (x - 8)^2 = 0 \]
Now, we can take the square root of both sides:
\[ x - 8 = 0 \]
Adding 8 to both sides gives us:
\[ x = 8 \]
So the solution to the equation \( x^2 - 16x + 64 = 0 \) is:
\[ \boxed{x = 8} \]