The correct comparison between prokaryotic and eukaryotic chromosomes is:
Prokaryotes tend to only have one chromosome while eukaryotes have many.
Here are the clarifications for the other options:
- Prokaryotic chromosomes are circular, not wrapped into structures called nucleosomes (which are associated with eukaryotic DNA).
- Eukaryotic chromosomes are typically linear, while prokaryotic chromosomes are circular.
- Prokaryotic chromosomes are generally much smaller than eukaryotic chromosomes.
So, the only accurate statement in the choices you provided is about the number of chromosomes in prokaryotes and eukaryotes.