Question
Sickle-cell anemia is caused by a change in a single amino acid in the polypeptide chain.
A change in which level of protein structure accounts for this condition?
Responses
primary
primary
tertiary
tertiary
quaternary
quaternary
secondary
A change in which level of protein structure accounts for this condition?
Responses
primary
primary
tertiary
tertiary
quaternary
quaternary
secondary
Answers
GPT-4o mini
The correct response is **primary**.
Sickle-cell anemia is caused by a mutation in the gene that encodes the beta chain of hemoglobin, resulting in the substitution of valine for glutamic acid at the sixth position of the polypeptide chain. This change at the level of the amino acid sequence is a change in the primary structure of the protein.
Sickle-cell anemia is caused by a mutation in the gene that encodes the beta chain of hemoglobin, resulting in the substitution of valine for glutamic acid at the sixth position of the polypeptide chain. This change at the level of the amino acid sequence is a change in the primary structure of the protein.