To solve the equation \(8^{x+1} = 16^{2x-4}\), we start by expressing both bases as powers of 2.
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Rewrite \(8\) and \(16\): \[ 8 = 2^3 \quad \text{and} \quad 16 = 2^4 \] Thus, we can rewrite the equation as: \[ (2^3)^{x+1} = (2^4)^{2x-4} \]
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Using the property of exponents \((a^m)^n = a^{m \cdot n}\): \[ 2^{3(x+1)} = 2^{4(2x-4)} \]
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This simplifies to: \[ 2^{3x + 3} = 2^{8x - 16} \]
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Since the bases are the same, we can set the exponents equal to each other: \[ 3x + 3 = 8x - 16 \]
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Now, solve for \(x\): \[ 3 + 16 = 8x - 3x \] \[ 19 = 5x \] \[ x = \frac{19}{5} \]
Therefore, the solution is: \[ \boxed{\frac{19}{5}} \]
So the correct option is D: \(x = \frac{19}{5}\).