The best response to explain why the economy in the New England Colonies was different from the economy in the Middle Colonies is: The settlers in the Middle Colonies used resources from the forest to trade for needed goods.
This response accurately reflects the economic activities in the Middle Colonies, which included a mix of agriculture and trade, taking advantage of their natural resources. In contrast, New England's economy was heavily influenced by its rocky terrain and colder climate, leading to a focus on fishing, shipbuilding, and trade rather than large-scale agriculture.