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The correct formal way to ask "how are you?" in Spanish is "驴C贸mo est谩?" (option A), using the formal second-person singular "usted."
So, the answer is **A. Coma esta** (though the correct spelling is "驴C贸mo est谩?"). Option B ("驴C贸mo estas?") is informal and used with "t煤."
Therefore, only option A is appropriate for a formal context.