Question
Part A
Use the following information to answer the following question.
"The native structure of hemoglobin (HB) comprises of two α and two β subunits, each of which carries a heme group. There appear to be no previous studies that report the in-vitro folding and assembly of Hb from highly unfolded α and β globin in a 'one-pot' reaction. One difficulty that has to be overcome for studies of this kind is the tendency of Hb to aggregate during refolding. This work demonstrates that denaturation of Hb in 40% acetonitrile at pH 10.0 is reversible." (J Am Soc Mass Spectrum 2007, 18, 8-16)
Which of the following statements about hemoglobin is most consistent with the information in the passage?
a quaternary protein with two polypeptides
a quaternary protein with four polypeptides
a tertiary protein with four polypeptides
a tertiary protein with two polypeptides
Use the following information to answer the following question.
"The native structure of hemoglobin (HB) comprises of two α and two β subunits, each of which carries a heme group. There appear to be no previous studies that report the in-vitro folding and assembly of Hb from highly unfolded α and β globin in a 'one-pot' reaction. One difficulty that has to be overcome for studies of this kind is the tendency of Hb to aggregate during refolding. This work demonstrates that denaturation of Hb in 40% acetonitrile at pH 10.0 is reversible." (J Am Soc Mass Spectrum 2007, 18, 8-16)
Which of the following statements about hemoglobin is most consistent with the information in the passage?
a quaternary protein with two polypeptides
a quaternary protein with four polypeptides
a tertiary protein with four polypeptides
a tertiary protein with two polypeptides
Answers
GPT-4o mini
The statement that is most consistent with the information in the passage is:
**a quaternary protein with four polypeptides.**
This is because hemoglobin (Hb) is composed of two α and two β subunits, totaling four polypeptide chains, making it a quaternary protein.
**a quaternary protein with four polypeptides.**
This is because hemoglobin (Hb) is composed of two α and two β subunits, totaling four polypeptide chains, making it a quaternary protein.