The correct answer is:
a inadequate supply of oxygen to muscle cells leads to lactic acid fermentation.
When you run as fast as you can, your muscles require a lot more energy than normal. During intense exercise, the demand for oxygen can exceed the supply available to the muscle cells. As a result, the cells shift from aerobic respiration, which uses oxygen to produce energy, to anaerobic respiration (lactic acid fermentation) to generate ATP in the absence of sufficient oxygen. This process produces lactic acid as a byproduct, which accumulates in the muscles and contributes to the burning sensation and fatigue experienced during intense physical activity.