To evaluate \(4^2 \times 4^2\), we can first simplify each part:
\[ 4^2 = 16 \]
Now substituting back into the expression:
\[ 4^2 \times 4^2 = 16 \times 16 \]
Calculating \(16 \times 16\):
\[ 16 \times 16 = 256 \]
Alternatively, we can use the property of exponents that states \(a^m \times a^n = a^{m+n}\):
\[ 4^2 \times 4^2 = 4^{2+2} = 4^4 \]
Calculating \(4^4\):
\[ 4^4 = 256 \]
Thus, the final answer is:
\[ \boxed{256} \]