To simplify the expression \( 2(k - 4) - 3(2k - 1) \), we can follow these steps:
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Distribute the terms in the parentheses: \[ 2(k - 4) = 2k - 8 \] \[ -3(2k - 1) = -6k + 3 \]
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Combine the results: \[ 2k - 8 - 6k + 3 \]
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Combine like terms: \[ (2k - 6k) + (-8 + 3) = -4k - 5 \]
Therefore, the final result is: \[ \boxed{-4k - 5} \]