To perform the operation \((3x^2 - 10x - 2) - (6x + 3)\), we first distribute the negative sign across the second expression:
\[ 3x^2 - 10x - 2 - 6x - 3 \]
Next, we combine like terms. The like terms are the \(x\) terms and the constant terms:
- For the \(x\) terms: \(-10x - 6x = -16x\)
- For the constant terms: \(-2 - 3 = -5\)
Now, we can rewrite the expression by combining all parts:
\[ 3x^2 - 16x - 5 \]
So, the result of the operation \((3x^2 - 10x - 2) - (6x + 3)\) is:
\[ \boxed{3x^2 - 16x - 5} \]